Evaluation of Anthelmintic and Antimicrobial Activity of the Leaves of Lantana camara

Abstract

The anthelmintic activity and antimicrobial activity of petroleum ether, chloroform, ethanol and aqueous extract of leaves of Lantana camara were evaluated separately and the activities were compared with that of Albendazole and chloramphenicol. The petroleum ether, chloroform and aqueous extract exhibit dose dependent activity and the ethanol extract showed remarkable anthelmintic activity .In case of antimicrobial activity chloroform and aqueous extract exhibit dose dependent activity and petroleum ether extract and ethanol extract showed remarkable antimicrobial activity in case of Staphylococcus aureus and Escherichia coli (E.Coli). In the present study, in vitro antibacterial activity of petroleum ether, chloroform, ethanolic and aqueous extracts of the leaves of Lantana camara were studied using agar well diffusion method. Antibacterial efficacy of the extracts on Staphylococcus aureus, Bacillus subtilis and Escherechia coli was investigated. Among the solvents used chloroform extract alone exhibited antibacterial activity against all the strains used in the study. E.coli was more or less equally sensitive to all the extracts and chloramphenicol (positive control) while Staphylococcus aureus was resistant to ethanolic extract. Petroleum ether and aqueous extracts did not produce zone of inhibition against Bacillus subtilis.